Health and Nutrition

January 23, 2013

Vitamin D and Type 2 Diabetes

Filed under: Diet,Vitamin D — Doc Joe @ 4:29 pm

Journal of Diabetes, 01/23/2013  Clinical Article

Xuan Y et al. – Observational studies have revealed an inverse association between vitamin D deficiency and incident type 2 diabetes (T2D). More double–blind randomized control studies that investigate the effects of vitamin D supplementation on insulin sensitivity, insulin secretion and the occurrence of T2D are needed.

  • Based on increasing evidence from animal and human studies, vitamin D deficiency is now regarded as a potential risk factor for T2D.
  • Vitamin D is involved in the pathogenesis of pancreatic ?–cell dysfunction, insulin resistance and systemic inflammation, conditions that contribute to the development of T2D.
  • Vitamin D can affect the progress of this disease directly through the activation of its own receptor and indirectly via the regulation of calcium (Ca) homeostasis

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