Health and Nutrition

January 31, 2013

Vitamin D as possible breast cancer treatment

Filed under: Cancer,Vitamin D — Doc Joe @ 4:08 pm

24 January 2013

A study published this last week in the Journal of Cell Biology reports that researchers have uncovered a molecular pathway that contributes to triple-negative breast cancer, a deadly and treatment resistant form of cancer that often occurs in young women. And more yet, vitamin D might be involved in this molecular pathway. A molecular pathway is a series of actions among molecules in a cell that lead to a change in that cell.

Lead author Susan Gonzalo, PhD, Assistant Professor of Biochemistry and Molecular Biology at Saint Louis University and colleagues also identified vitamin D as a possible new cancer therapy, in addition to discovering three biomarkers that will help identify patients who may benefit from the new treatment.

Read the rest of the article

January 23, 2013

Vitamin D and Type 2 Diabetes

Filed under: Diet,Vitamin D — Doc Joe @ 4:29 pm

Journal of Diabetes, 01/23/2013  Clinical Article

Xuan Y et al. – Observational studies have revealed an inverse association between vitamin D deficiency and incident type 2 diabetes (T2D). More double–blind randomized control studies that investigate the effects of vitamin D supplementation on insulin sensitivity, insulin secretion and the occurrence of T2D are needed.

  • Based on increasing evidence from animal and human studies, vitamin D deficiency is now regarded as a potential risk factor for T2D.
  • Vitamin D is involved in the pathogenesis of pancreatic ?–cell dysfunction, insulin resistance and systemic inflammation, conditions that contribute to the development of T2D.
  • Vitamin D can affect the progress of this disease directly through the activation of its own receptor and indirectly via the regulation of calcium (Ca) homeostasis

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