Health and Nutrition

May 9, 2009

Green Tea Extract May Improve Recovery from Injury

Filed under: General Health,Herbal Remedies,Nutrition — Doc Joe @ 4:28 pm

Breaking News

In a recently published study, green tea extract was investigated in an experimental model of spinal cord injury.

In this study, mice were subjected to spinal cord trauma by a spinal operation called a laminectomy, in which the area of the vertabrae called the lamina is removed. This operation resulted in increased measures of inflammation and edema, infiltration of white blood cells called neutrophils, and programmed cell death, also known as apoptosis. There were also significantly increased levels of nitrotyrosine, which is used as a marker of cell damage, inflammation, and nitric oxide production. Green tea extract was administered one and six hours after the spinal cord injury.

The mice receiving green tea extract demonstrated a reduction in all of the measures of inflammation. There was a significant decrease in the degree of spinal cord inflammation and reductions in levels of nitrotyrosine, less infiltration by neutrophils, and lower levels of poly ADP-ribosyl synthetase, which is an enzyme involved in apoptosis and DNA repair. Additionally, the recovery of limb function was significantly ameliorated by green tea extract.

The study authors stated, “Taken together, our results clearly demonstrate that green tea extract treatment ameliorates spinal cord injury oxidative stress.”

Reference:

Paterniti I, Genovese T, Crisafulli C, Mazzon E, Di Paola R, Galuppo M, Bramanti P, Cuzzocrea S. Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma. Naunyn Schmiedebergs Arch Pharmacol. 2009 Apr 1. Published Online Ahead of Print.

Individuals who do not want to consume large amounts of green tea as a beverage can take green tea extract capsules

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