Health and Nutrition

December 17, 2018

The effect of curcumin (turmeric) on Alzheimer’s disease: An overview

Filed under: General Health,Herbal Remedies,Nutrition — Doc Joe @ 4:49 pm

Ann Indian Acad Neurol. 2008 Jan-Mar; 11(1): 13–19.doi:  [10.4103/0972-2327.40220: 10.4103/0972-2327.40220]PMCID: PMC2781139PMID: 19966973

Shrikant Mishra and Kalpana PalaniveluDepartment of Neurology, VA/USC 16111, Sepulveda, CA, USAFor correspondence: Shrikant Mishra, Department of Neurology, VA/USC 16111, Plummer Street, Sepulveda, CA, 91343 USA. E-mail: ude.csu@arhsimsReceived 2007 Nov 4; Revised 2008 Feb 5; Accepted 2008 Feb 12

Abstract

This paper discusses the effects of curcumin on patients with Alzheimer’s disease (AD). Curcumin (Turmeric), an ancient Indian herb used in curry powder, has been extensively studied in modern medicine and Indian systems of medicine for the treatment of various medical conditions, including cystic fibrosis, haemorrhoids, gastric ulcer, colon cancer, breast cancer, atherosclerosis, liver diseases and arthritis. It has been used in various types of treatments for dementia and traumatic brain injury. Curcumin also has a potential role in the prevention and treatment of AD. Curcumin as an antioxidant, anti-inflammatory and lipophilic action improves the cognitive functions in patients with AD. A growing body of evidence indicates that oxidative stress, free radicals, beta amyloid, cerebral deregulation caused by bio-metal toxicity and abnormal inflammatory reactions contribute to the key event in Alzheimer’s disease pathology. Due to various effects of curcumin, such as decreased Beta-amyloid plaques, delayed degradation of neurons, metal-chelation, anti-inflammatory, antioxidant and decreased microglia formation, the overall memory in patients with AD has improved. This paper reviews the various mechanisms of actions of curcumin in AD and pathology.

Keywords: Alternative approach to Alzheimer’s, beta amyloid plaques, curcumin, curcumin and dementia, epidemiology, turmeric

March 3, 2016

Higher Vitamin D Levels Reduce Cancer Death Rates up to 52%

Filed under: Cancer,Diet,Nutrition — Doc Joe @ 2:51 pm

The Journal of Clinical Endocrinology & Metabolism published a meticulous analysis of past trials showing that patients with colorectal cancer, breast cancer, and lymphoma experienced a significantly reduced risk of mortality with higher serum vitamin D levels at diagnosis compared to those with low levels.*

Researchers selected 25 studies involving 17,332 cases of cancer for their meta-analysis.

Compared to lowest quartile, those with vitamin D levels in the top 25% range at the time of diagnosis had far better survival outcomes. For each of the following cancers, the risk of dying decreased by:

  • 37% for breast cancer patients
  • 45% for colorectal cancer patients
  • 52% for lymphoma patients

“By reviewing studies that collectively examined vitamin D levels in 17,332 cancer patients, our analysis demonstrated that vitamin D levels are linked to better outcomes in several types of cancer,” stated Dr. Hui Wang, MD, PhD, Professor of the Institute for Nutritional Sciences at the Shanghai Institutes for Biological Sciences at the Chinese Academy of Sciences in Shanghai. “The results suggest vitamin D may influence the prognosis for people with breast cancer, colorectal cancer, and lymphoma, in particular.”

Researchers found the strongest links between vitamin D levels and survival in breast cancer, lymphoma, and colorectal cancer. There was less evidence of a connection in people with lung cancer, gastric cancer, prostate cancer, leukemia, melanoma, or Merkel cell carcinoma.

Editor’s Note: Meta-analysis shows 4% reduction in death for all causes for every 4 ng/mL increase in circulating 25-OH vitamin D levels within the range the researchers examined. Serum vitamin D levels in those who don’t supplement are often below 13 ng/mL. By increasing vitamin D intake to 10,000 to 15,000 IU a day, optimal serum levels of 50 to 80 ng/mL can be achieved.

Reference
* JCEM . 2014 Apr 29.

March 20, 2015

The Forgotten Longevity Benefits of Taurine

Filed under: Diet,General Health,Nutrition,Supplements — Doc Joe @ 10:02 pm

Taurine: Bountiful Benefits

  • Taurine is the most abundant amino acid you’ve never heard of; it is found throughout the body, but especially in tissues containing excitable cells, like nerves and heart muscle.
  • Strong epidemiological evidence suggests that certain groups with the longest life spans consume higher amounts of taurine than those of us in the rest of the world.
  • Taurine supplementation can prevent diabetes and obesity in animal models, and can mitigate the effects of both conditions in humans.
  • Taurine supplementation strengthens heart muscle cells, extends their life spans, and protects them from damage, while reducing many of the factors that produce atherosclerosis and its deadly consequences.
  • Taurine protects retinal and inner ear cells from damage, normalizing the flow of calcium ions they require for proper function.
  • Evidence is growing for taurine’s role in preventing epileptic seizures and liver disease, two conditions that can be attributed to toxic effects on delicate tissue.
  • If you are interested in a longer, healthier, and more active life, consider supplementing with taurine.

(more…)

Magnesium – a secret weapon against diabetes

Filed under: General Health,Nutrition,Supplements — Doc Joe @ 2:15 pm

How can magnesium help you in the fight against diabetes?

Magnesium is a mineral that is essential to good health and necessary for more than 300 biochemical reactions within the body. Some of its more critical jobs include maintaining muscle and nerve function, as well as immune function and blood glucose control.

Magnesium has a close relationship with insulin. Insulin is a hormone that delivers glucose to the body’s cells. Without magnesium, insulin is unable to perform this function, resulting in high blood glucose levels. A deficiency in magnesium may create a resistance to insulin and without the necessary levels of magnesium, the larger amounts of insulin produced to maintain glucose levels are not accommodated.

People with diabetes tend to have inadequate amounts of magnesium and also have additional loss of magnesium in their urine. This can intensify the health conditions and complications

Research shows that low magnesium levels may further promote progression of diabetes. Surveys have indicated that many adults do not meet the recommended daily intake of magnesium. There are many nutrient-dense foods that contain rich amounts of magnesium in them.

Magnesium can be found in foods such as dry roasted almonds, spinach, cashews, peanut butter and baked potatoes. Skim milk also contains magnesium. Check the 2010 dietary guidelines for more information on magnesium and its recommendations. Also visit Michigan State University Extension online for more interesting and useful articles related to diabetes and nutrition.

February 11, 2015

Vitamin D status may impact stroke severity

Filed under: General Health,Nutrition,Supplements — Doc Joe @ 3:23 pm
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Past studies have already linked the vitamin D status to many diseases. US researchers have now found an association to severity of stroke and subsequent recovery. The lower the vitamin D level, the more severe the stroke and the poorer the recovery, reported scientists at the “International Stroke Conference 2015” of the American Stroke Association in Nashville (Tennessee).

The study, carried out by the University of Massachusetts in Worchester, included 96 patients who were treated between January 2013 and January 2014 after suffering a stroke. Study subjects with low vitamin D levels (25-hydroxyvitamin D below 30 nanograms per millilitre of blood) had areas of dead tissue that was twice as large as that found in patients with normal vitamin D status. This affected both patients with lacunar and with non-lacunar strokes.

The vitamin D level also affected the recovery following a stroke. For each 10 ng/ml reduction in 25-hydroxyvitamin D the chance of recovery within three months following a stroke decreased by half. Stroke severity and the age of the patients did not play a role.

Since the study only involved a small number of mainly Caucasian study participants, it was too early to draw firm conclusions, the authors conceded. Nevertheless, patients should seek advice from their physicians regarding the need for vitamin D supplementation, particularly if they have an elevated risk of stroke, the authors recommended. Further studies were needed.

 

January 7, 2015

Gluten: What You Dont Know Might Kill You

Filed under: Diet,General Health,Nutrition — Doc Joe @ 10:40 pm

January 2, 2015

Sunlight Holds Key To Killing Breast Cancer

Filed under: Cancer,Diet,General Health,Nutrition — Doc Joe @ 1:20 am

December 31, 2014

This Fatty Food Promotes A Healthy Heart And Waistline?

Filed under: Diet,General Health,Nutrition — Doc Joe @ 3:51 pm

December 30, 2014

Grape seed extract is a powerful antioxidant

Filed under: General Health,Herbal Remedies,Nutrition — Doc Joe @ 6:55 pm

December 12, 2014

An easier to understand video by Dr. Lustig

Filed under: Diet,General Health,Nutrition — Doc Joe @ 10:58 pm

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